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Hetchyn Biotechnology headquarters
HETCHYNBIOTECH

Co., Ltd — Jiaxing, Zhejiang, China

Global Leader in Glass-Greenhouse Cultivation of Dunaliella salina

🌐 hetchyn.com Company Website 🛒 9cis.com 9-cis Shop ✉ info@hetchyn.com Email Us
01 · Company Overview

Global Leader in Glass-Greenhouse Cultivation of Dunaliella salina

  • —HQ in Jiaxing, Zhejiang, China — full supply-chain algae biotech company
  • —World's largest glass-greenhouse raceway-pond Dunaliella salina facility
  • —End-to-end: strain cultivation → spray-dried powder → supercritical CO₂ oil → softgels
  • —Founded by Dr. Nancy Xu — 10+ years of expertise, 2× world-class patents
TopGlass-greenhouse producer globally
~100 haScale by 2027
0Discharge
Self-GRASGMP ISO 9001ISO 22000 HACCPKosher
Hetchyn facility exterior
Jiaxing Facility
Hetchyn glass greenhouse interior
Glass-Greenhouse Interior
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com · hetchyn.com | 9cis.com01 / 15
02 · Founder Spotlight
Dr. Nancy Xu in laboratory holding algae flask
Lab Research
Dr. Nancy Xu in greenhouse with algae sample
Greenhouse Operations

Dr. Nancy Xu

Founder & Chief Scientist · Hetchyn Biotechnology

10+ Years
Deep expertise in Dunaliella salina research & cultivation
World-Class Patents
International patents in glass-greenhouse cultivation & 9-cis enrichment
Pioneer in Glass Greenhouse
First stable, large-scale indoor raceway cultivation system
9-cis β-Carotene Specialist
Precision control of carotenoid isomer ratios at commercial scale
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com02 / 15
03 · Industry Pain Points

Traditional Cultivation Falls Short

Outdoor open-pond & salt-lake methods expose producers to uncontrollable risks

✕
Weather Dependence
No year-round stability — production disrupted by seasons & temperature swings
✕
Bacterial Contamination
Open-air exposure leads to inconsistent purity and supply interruptions
✕
Heavy Metal Exceedance
Arsenic concentration fails EU / US / JP international standards
✕
Low 9-cis Content
Uncontrolled conditions yield mostly all-trans isomer with lower bioavailability
Aerial view of traditional open outdoor pond cultivation
Traditional Open Ponds
Natural salt lake cultivation — weather dependent
Natural Salt Lakes
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com03 / 15
04 · Our Solution
Hetchyn glass greenhouse raceway pond interior — green algae

Intelligent Glass Greenhouse

Year-Round Stable Production
365 days, zero seasonal disruption
Physical Isolation — Zero Contamination
Pharmaceutical-grade purity guaranteed
Precision-Controlled 9-cis Enrichment
Light, temperature & salinity tuned to maximise 9-cis yield
Heavy Metals Below Detection Limit
Total arsenic undetected — EU / US / JP fully compliant
Zero Discharge Closed Loop
Brine and nutrients fully recycled — a worldwide first
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com04 / 15
05 · Inside Our Facility

The World's Cleanest Algae Cultivation Environment

Amber-coloured Dunaliella salina raceway pond — rich in β-carotene
Glass greenhouse raceway interior with automated paddlewheel mixing
Close-up of amber algae raceway with precision water control

Enclosed glass-greenhouse raceways — no weather exposure, no contamination, year-round harvest

Hetchyn Biotechnology Co., Ltd · info@hetchyn.com05 / 15
06 · Production Process · Cultivation & Harvest

From Strain to Powder — Every Stage Controlled

Proprietary Dunaliella salina strain cultivation in lab flasks
01
Strain Lab
Proprietary high-9-cis strains cultivated under sterile conditions
Medium-scale cultivation scale-up vessels
02
Scale-Up Cultivation
Intermediate vessels progressively scale strain volume before raceway
Nutrient and feed mixing system
03
Feed & Nutrient System
Automated nutrient mixing and dosing for optimal algae growth
Full-scale glass greenhouse raceway pond
04
Full Raceway Pond
Enclosed raceway ponds with precision light, temp & salinity control
Industrial centrifuge harvesting unit
05
Centrifuge
Industrial centrifugation concentrates biomass, minimising oxidation
Spray drying industrial tanks
06
Spray Drying
Low-temperature spray drying preserves 9-cis isomer integrity
Algae paste collection and transfer room
07
Collection Room
Clean-room collection and transfer of dried powder to packaging line
Final Dunaliella salina spray-dried powder — rich amber colour
08
Final Powder
High-9-cis β-carotene powder, packaged to spec
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com06 / 15
07 · Production Process · Extraction → Oil

Supercritical CO₂ Extraction & Quality Control

Supercritical CO2 extraction equipment
10
Supercritical CO₂ Extraction
Solvent-free extraction preserves heat-sensitive 9-cis isomers
QC analyst testing algae extract
11
Isomer Analysis
HPLC verification of 9-cis:all-trans ratio at each batch
QC laboratory team conducting multi-parameter testing
12
Multi-Parameter QC
Heavy metals, potency, microbiology tested by in-house lab team
Dunaliella salina oil — final product
13
Dunaliella Oil
1% / 5% / 10% oil; 9-cis:all-trans ≥ 1:1, up to 4:1 on request
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com07 / 15
08 · Scale

3 ha Today. 100 ha by 2027.

Now
3 ha — Operational at Full Capacity
Glass greenhouse raceways running at maximum productivity
2026
+20 ha — Under Construction
New phase under construction, delivery end 2026 → total 30 ha
2027
+70 ha — Planned Expansion
World's largest Dunaliella salina facility — 100 ha total
Aerial view of current 3ha Hetchyn glass greenhouse facility
Now — 3 ha Operational
Architectural rendering of 30ha facility expansion by 2026
By 2026 — 30 ha Rendering
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com08 / 15
09 · Sustainability & ESG

Globally Unique Zero-Emission Process

0
Discharge
Closed-loop water recycling. Zero liquid discharge — a worldwide first in algae cultivation.
CO₂↓
Net Carbon Capture
Carbon-negative production by design — algae continuously absorb CO₂ during growth.
AI
Smart Greenhouse
AI-driven IoT sensors, intelligent energy management, minimal resource waste.

Hetchyn's ESG performance is not a marketing claim — it is an engineering outcome.

Closed-loop water recycling system diagram
Closed-Loop Recycling System
Water recycling infrastructure at Hetchyn facility
Recycling Infrastructure
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com09 / 15
10 · Certifications & Quality

Certified for Global Markets

GMP
ISO 9001
ISO 22000
HACCP
Self-GRAS
ISO 14001
ISO 45001
✡ Kosher

Green Factory certification in progress · Self-GRAS final submission in progress

Hetchyn Biotechnology Co., Ltd · info@hetchyn.com10 / 15
11 · Core Product Portfolio

Three Product Lines, One Source of Truth

Dunaliella salina powder — bulk ingredient
Dunaliella salina Powder
Bulk ingredient · Custom specification
High 9-cis:all-trans ratio · Spray-dried
Dunaliella salina oil — 1% 5% 10% concentrations
Dunaliella salina Oil
Supercritical CO₂ extracted
1% / 5% / 10% concentrations
9-cis:all-trans ≥ 1:1 · up to 4:1 on request
Natural 9-cis beta carotene softgel capsules
Natural 9-cis Softgel
5 mg 9-cis per capsule · 30 caps/box
Available at 9cis.com
$129 / box
Hetchyn Biotechnology Co., Ltd · 9cis.com11 / 15
12 · 9-cis Advantage

Not All β-Carotene Is Created Equal

Industry Standard (All-Trans)
Synthetic or open-pond derived
Predominantly all-trans isomer (~95%)
Lower bioavailability & absorption
Limited to cosmetic / food applications
Heavy metal contamination risk (5–7 ppm As)
VS
Hetchyn Natural 9-cis
Glass-greenhouse cultivated — natural origin
Rich in 9-cis isomer (≥ 1:1, up to 4:1 on request)
Significantly higher bioavailability & activity
Approved for Phase II medical clinical trials
Total arsenic < 0.5 ppm — EU / US / JP compliant

The 9-cis isomer is the biologically active form found in nature. Only Hetchyn supplies it at scale. · Applications: Retinitis Pigmentosa · Immune Support · Arteriosclerosis

Hetchyn Biotechnology Co., Ltd · info@hetchyn.com12 / 15
13 · Clinical Partnership
SHEBA MEDICAL CENTER Tel HaShomer, Israel · Top 10 Hospital Globally

Phase II Clinical Trials Underway

Retinitis Pigmentosa (RP) — Phase II
Using Hetchyn high-9-cis oil capsules. Human subject recruitment actively underway.
Arteriosclerosis — Animal Phase
Results dramatically exceed Phase I outcomes. Human trial preparation in progress.
Superior Absorption — Why Sheba Chose Us
Hetchyn's high-9-cis formulation delivers significantly greater bioavailability than market alternatives.
Exclusive Trial Softgels
Hetchyn providing proprietary softgels formulated specifically for Sheba's Phase II protocols.
Phase II
Clinical Trials
Retinitis Pigmentosa
Sheba Medical Center
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com13 / 15
14 · Future Vision

To Be the Largest Dunaliella salina Producer on Earth

Making pharmaceutical-grade natural 9-cis β-carotene universally accessible.

2025
Operations & Partnerships
  • 3 ha operational at full capacity
  • B2B supply agreements active
  • Sheba Phase II preparations ongoing
2026
Scale to 30 ha
  • +20 ha delivery end 2026
  • 9cis.com D2C channel live
  • Global supply agreements signed
  • Sheba Phase II human trials active
  • Expanded product range launched
2027
100 ha — World Leader
  • Largest Dunaliella salina producer on Earth
  • +70 ha additional expansion complete
  • Global distribution network established
  • Pharmaceutical-grade supply at scale
Hetchyn Biotechnology Co., Ltd · info@hetchyn.com14 / 15
Thank You
HETCHYN

BIOTECHNOLOGY CO., LTD

Global Leader in Glass-Greenhouse Cultivation of Dunaliella salina.
Natural 9-cis β-Carotene — at scale, at purity, for the world.

hetchyn.com Company Website
9cis.com Product Website
info@hetchyn.com General Enquiries

Dr. Nancy Xu · Founder & Chief Scientist · Jiaxing, Zhejiang, China